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WebApr 4, 2024 · ACTIVE. Spherox. EU number: EU/1/17/1181. Active substance: spheroids of human autologous matrix-associated chondrocytes. Indication: Repair of symptomatic articular cartilage defects of the femoral condyle and the patella of the knee (International Cartilage Regeneration & Joint Preservation Society [ICRS] grade III or IV) with defect … WebJul 9, 2024 · The choice of method depends on the size of the defect, the condition of the cartilage and the patient (age, weight, history, functional demand). In France, the most commonly used methods are mosaicoplasty, microfractures (alone or with membrane cover) and osteochondral allograft. Mosaicoplasty is the reference technique for defects … WebSpheroids of human autologous matrix-associated chondrocytes, sold under the brand name Spherox, is a medication used to repair defects to the cartilage in the knee in adults who … cumbria places of interest