WebPoly(rC) binding protein 2 (PCBP2) forms a specific ribonucleoprotein (RNP) complex with the 5'-terminal sequences of poliovirus genomic RNA, as determined by electrophoretic mobility shift assay. WebNov 24, 2015 · The poly(rC)-binding protein 2 (PCBP2) is currently reported to inhibit cardiac hypertrophy.However, how PCBP2 is regulated at transcriptional level remains unknown. Here, we show that Meis1, a PBX1-related homeobox gene, binds to PCBP2 promoter and promotes its transcription.In human failing heart tissues and murine hypertrophic heart …
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WebAug 18, 2024 · Investigator at NIA with interest in aging, geroscience, mass spectrometry, proteomics, senescence, PTMs, biomarkers, data-independent acquisition, protein turnover. Former K99-recipient and ... WebSynonym(s): Anti-LIP4, Anti-LYST-interacting protein, Anti-MCG10, Anti-RNA binding protein MCG10, Anti-poly(rC) binding protein 4 curled lob
Multilevel regulation and molecular mechanism of poly …
WebOct 16, 2024 · Abstract. Poly (rC)-Binding Protein-1 (Pcbp1) belongs to the KH homology superfamily of nucleic acid-binding proteins, which has been implicated in a vast array of biological processes such as iron transport, RNA processing, post-transcriptional and translational regulations. Germline deletion of Pcbp1 results in embryonic lethality before ... Webpoly(rC) binding protein 3. Synonyms. AlphaCP-3 Feature Type. protein coding gene. IDs. MGI:1890470 NCBI Gene: 59093. Alliance. gene page. Transcription Start Sites. 7 TSS. Location & Maps more. Sequence Map Chr10:76597691-76797721 bp, - strand. From Ensembl annotation ... WebNov 14, 2024 · Poly(rC)-binding proteins (PCBPs), a defined subfamily of RNA binding proteins, are characterized by their high affinity and sequence-specific interaction with … curled locs