Coupled-clock theory
http://isl.stanford.edu/~abbas/ee392b/lect02.pdf WebMar 12, 2024 · Three theories are proposed: M-clock theory, Ca 2+ clock theory, and coupled clock theory, described here in brief: M-clock theory: this theory, known as membrane clock (or just briefly M clock), implicates that ion channels and ion transporters located on the myocardial cell membrane, their inward and outward currents, and their …
Coupled-clock theory
Did you know?
WebApr 1, 2014 · Data interpretation and future directions to address the problem are given within the coupled-clock theory, i.e., a modern view on the cardiac pacemaker cell function generated by a system of sarcolemmal and intracellular proteins. Keywords: CaMKII; calcium; cardiac pacemaker; ion channels ... WebFeb 23, 2015 · These results provide evidence that supports the coupled-clock theory, demonstrating the ability of the LCR Ca 2+ signal to report the degree of synchronization …
WebJul 26, 2024 · Our review is focused on the evolution of experimental definition and numerical modeling of the coupled-clock concept, on how mechanisms intrinsic to pacemaker cell determine both the heart rate... WebJul 17, 2013 · Data interpretation and future directions to address the problem are given within the coupled-clock theory, i.e., a modern view on the cardiac pacemaker cell function generated by a system of ...
WebThe coupled-clock theory postulates that the DD is generated by the two coupled oscilla- tors, Ca 2+ -clock and M-clock, rather than just by M-clock alone (Figure 1). ... View in … WebJun 22, 2024 · The use of a uniaxial birefringent material such as lithium niobate $({\\mathrm{LiNbO}}_{3},\\phantom{\\rule{4pt}{0ex}}\\mathrm{LN})$ as the core of a …
WebThe coupled-clock theory postulates that the DD is generated by the two coupled oscilla- tors, Ca 2+ -clock and M-clock, rather than just by M-clock alone (Figure 1). ... View in full-text Context 4
WebThis review summarizes the present state of numerical modeling of the cardiac pacemaker, including approaches to resolve present paradoxes and controversies. Specifically we … stan court recordsWebMar 29, 2016 · The right panel depicts the oscillation frequency for an uncoupled clock, which is 0.5003 [Hz], whereas the left panel shows the oscillation frequency for the coupled clocks, which is 0.4935 [Hz]. persona dancing all night collectionWebOct 22, 2013 · synchronization with an arbitrary phase shift. no synchrony. In a classical context, synchronization (from Greek syn = the same, common and chronos = time) … stan co whos in jailWebOct 22, 2013 · synchronization with an arbitrary phase shift. no synchrony. In a classical context, synchronization (from Greek syn = the same, common and chronos = time) means adjustment of rhythms of self-sustained periodic oscillators due to their weak interaction; this adjustment can be described in terms of phase locking and frequency entrainment. stan covey harrison idahoWebJan 1, 2014 · Specifically we discuss the requirement for realistic modeling to consider symmetrical importance of both intracellular and cell membrane processes (within a recent “coupled-clock” theory). Promising future developments of the complex pacemaker system models include the introduction of local calcium control, mitochondria function, … persona dancing all night soundtrackWebMay 22, 2024 · Abstract. This chapter presents a formalism for showing that small changes in the structure of an optical waveguide structure can couple optical fields, as they … stan covingtonWebThe Coupled-Clock Theory Explains, in Part, the Effect of Heterogenous Cell Populations to Enhance Robustness of SAN Function The coupled-clock theory ( Maltsev and Lakatta, 2009 ) postulates that the intrinsic cell automaticity is defined by a combined and synergistic action of the Ca and membrane clocks as depicted in the P up - g CaL diagram ... stan coward obituary