WebJul 29, 2005 · Phosphotriesterase (PTE) is a binuclear metalloenzyme that catalyzes the hydrolysis of organophosphates, including pesticides and chemical warfare agents, at rates approaching the diffusion controlled limit. The catalytic mechanism of this enzyme features a bridging solvent molecule that is proposed to initiate nucleophilic attack at the … WebFeb 3, 2024 · Abstract. There are potential applications for binuclear oxo-bridged iron complexes in biological processes, catalysts, and magnetic materials, and the design of …
RCSB PDB - 1D3V: CRYSTAL STRUCTURE OF THE BINUCLEAR …
WebOct 1, 1999 · The crystal structure of the complex between the binuclear manganese metalloenzyme arginase and the boronic acid analog of L-arginine, 2(S)-amino-6 … WebJan 1, 2010 · Arginase is a binuclear manganese metalloenzyme that hydrolyzes L-arginine to form L-ornithine and urea, and aberrant arginase activity is implicated in various diseases such as erectile dysfunction, asthma, atherosclerosis, and cerebral malaria. Accordingly, arginase inhibitors may be therapeutically useful. city hall seattle washington
Human Arginase II: Crystal Structure and Physiological
WebApr 15, 2024 · Compared with the first two enzymes, the metalloenzyme of PTE has greater catalytic activity (Aubert et al., 2004). It could be a good option for degrading OPs. PTE is an enzyme that contains a binuclear metal center with two Zn ions, which are assigned as α and β at active sites, respectively (Aubert et al., 2004). The α metal is ... WebNov 26, 2003 · This microreview describes the structures, properties and mechanisms of three selected bimetallic enzymes: Cu-Zn superoxide dismutase (SOD), purple acid … WebHere, we demonstrated that the photolysis of a caged compound under cryogenic temperature followed by thermal annealing is an invaluable technique for trapping of short-lived reaction intermediates of metalloenzymes through the study of membrane-integrated nitric oxide reductase (NOR) that catalyzes reductive coupling of two NO molecules to … did athena ever have children